Filippini Giacomo

Giacomo Filippini
Staff/Student ID number: 
30968
Notes: 

 

Profile: Giacomo Filippini obtained his Master’s degree in Industrial Chemistry from the University of Bologna (Italy). Specifically, in the laboratory of Professor Giorgio Bencivenni, he studied the reactivity of α,β-unsaturated ketones using aminocatalytic strategies. In 2013, he joined the group of Prof. Paolo Melchiorre at ICIQ in Tarragona (Spain), where he undertook his doctoral studies. The main scientific objective of his doctoral research was to employ and combine two powerful fields of molecule activation, photochemistry and organocatalysis, to efficiently realize new carbon-carbon bond forming transformations in an environmentally friendly way. In 2015, he had the opportunity to join the group of Prof. Oliver Kappe at the University of Graz (Austria) for a research stay. In particular, he was involved in the development of photo-organocatalytic transformations under flow conditions. In October 2017, he successfully defended his PhD thesis and went on to take up a postdoctoral fellowship in the Carbon Nanotechnology Group headed by Professor Maurizio Prato at the University of Trieste. In 2023, he joined the Department of Chemical and Pharmaceutical Sciences (DSCF) of the University of Trieste as an Assistant Professor (RTD-b). In Trieste, his research activity is focused on the design and development of novel catalytic organic transformations which address unsolved problems in synthetic chemistry. The final goal of his scientific work is the production of effective, inexpensive and safe catalytic systems that will find widespread use in modern organic synthesis. In particular, he designed and developed new effective carbon-based nano-organocatalysts such as carbon nitrides and carbon dots. As a matter of fact, these metal-free materials have been efficiently used to drive relevant organic reactions, including enantioselective transformations, under mild operative conditions.

Awards and Recognitions: In 2014, he was the recipient of the XXIV Award "Guido Paolucci" as the best student of the School of Sciences at the Università di Bologna in the school year 2012-2013. In 2014, he could secure a highly competitive PhD fellowship awarded by the Spanish Ministry of Science, connected with the Severo Ochoa Excellence Accreditation program 2014–2018 (MINECO, SEV-2013-0319). Moreover, in 2022 he was selected as a "Young Researcher to Watch" by the international journal EurJOC, and in 2024 as "2024 Nanoscale Emerging Investigator" by the international journal Nanoscale. In 2023, he was selected as a Member of the European Cultural Institute "Accademia Marchigiana di Scienze, Lettere ed Arti". In 2024, he has been the recipient of the “Giacomo Ciamician” Medal of the Italian Chemical Society. In 2024, he received the national scientific habilitation to Associate Professorship of Organic Chemistry.

 

Areas of Expertise

 

● Organic Chemistry ● Photochemistry ● Asymmetric Catalysis ● Organocatalysis ● Radical Chemistry

● Materials Science ● Flow Chemistry

 

Research Overview: ​Our research activity aims at designing and developing novel catalytic organic transformations which address unsolved problems in synthetic chemistry. The final goal is therefore the production of effective, inexpensive and safe catalytic systems that will find widespread use in modern organic synthesis. Research work focuses on:

1. Photocatalysis with Aromatic Compounds: Recently, aromatic compounds have emerged as a reliable class of metal-free photoredox catalysts. Indeed, the great structural variety of these compounds combined with the easy fine-tuning of their electronic properties has unlocked new possibilities for the generation of reactive intermediates under mild operative conditions.

 2. Carbon Dots as Nano-Organocatalysts: Carbon nanodots (CDs) are photo-active carbon-based nanoparticles with sizes below 10 nm. Generally, CDs consist of carbon cores that are surrounded by shells containing numerous polar groups such as carboxylic acids, alcohols, and amines. Our research is focused on the study of CDs synthesis, characterization and modification for their use as (photo)catalysts in organic chemistry.

 3. Catalysis Based on 2D-Materials: Metal-free 2D nanomaterials possess high appeal due to their improved cost-effectiveness and lower toxicity with respect to many inorganic structures. The outstanding electronic characteristics of some metal-free 2D semiconductors have projected them into the world of organic synthesis, where they can function as catalysts to drive the sustainable synthesis of high-value organic molecules.

 

Selected Publications:

1. G. Filippini, M. Silvi, P. Melchiorre*, “Enantioselective Formal α-Methylation and α-Benzylation of Aldehydes by Means of Photo-Organocatalysis”, Angew. Chem. Int. Ed., 2017, 56, 4447-4451. 

2. C. Rosso, G. Filippini*, M. Prato*, “Carbon Dots as Nano-Organocatalysts for Synthetic Applications”, ACS Catalysis, 2020, 10, 8090-8105.

3. G. Filippini*, F. Amato, C. Rosso, G. Ragazzon*, A. Vega-Peñaloza, X. Companyó*, L. Dell’Amico, M. Bonchio, M. Prato*, “Mapping the Surface Groups of Amine-Rich Carbon Dots Enables Covalent Catalysis in Aqueous Media”, Chem, 2020, 6, 3022-3037.

4. G. Filippini, F. Longobardo, L. Forster, A. Criado, G. Di Carmine, L. Nasi, C. D’Agostino, M. Melchionna*, P. Fornasiero*, M. Prato*, “Light-Driven, Heterogeneous Organocatalysts for C-C-Bond Formation Towards Valuable Perfluoroalkylated Intermediates”, Sci. Adv., 2020, 6, eabc9923.

5. C. Rosso, G. Filippini, A. Criado, M. Melchionna*, P. Fornasiero, M. Prato*, “Metal-Free Photocatalysis: Two-Dimensional Nanomaterial Connection toward Advanced Organic Synthesis”, ACS  Nano, 2021, 15, 3621-3630.

6. C. Rosso, S. Cuadros, G. Barison, P. Costa, M. Kurbasic, M. Bonchio, M. Prato, L. Dell’Amico*, G. Filippini*, “Unveiling the Synthetic Potential of Substituted Phenols as Fully Recyclable Organophotoredox Catalysts for the Iodosulfonylation of Olefins”, ACS Catalysis, 2022, 12, 4290-4295.

7. M. Marchi, E. Raciti, S. M. Gali, F. Piccirilli, H. Vondracek, A. Actis, E. Salvadori, C. Rosso, A. Criado, C. D’Agostino, L. Forster, D. Lee, A. C. Foucher, R. K. Rai, D. Beljonne, E. A. Stach, M. Chiesa, R. Lazzaroni, G. Filippini*, M. Prato, M. Melchionna*, P. Fornasiero*, “Carbon Vacancies Steer the Activity in Dual Ni Carbon Nitride Photocatalysis”, Adv. Sci. 2023, 10, 2303781.

8. G. Gentile, M. Morant-Giner, L. Cardo, M. Melchionna, P. Fornasiero, M. Prato, G. Filippini*, “DoE-Assisted Development of a 2H-MoS2-Catalyzed Approach for the Production of Indole Derivatives”, ChemSusChem, 2023, e202300831.

 

For the full list of publications, please, refer to Google Scholar - link: https://scholar.google.com/citations?user=pMlMU8MAAAAJ&hl=it&oi=sra

Position: 
Fixed term researcher
Field: 
Organic Chemistry
Activities: 
Department's Board - Member
Boards of Studies - Member
Teaching staff - Teaching staff
Attachments: 
Programme Description Position
Chemistry.teachers Boards of Studies - Member
Pharmacy.teachers Boards of Studies - Member

Progetti

Research Project Position Status of Research Project
Photochemical Valorization of Phenols Research projects - Scientific Actor; Active
10%budget ricerca - Bernardi Andrea - Chimica XXXVIII Research projects - Scientific Actor; Active
Synthetic and Structural Synergy Towards Advanced Heterogeneous Photoredox Catalysis Research projects - Participant; Active
Progetto di Ateneo Microgrants Dr. Giacomo Filippini finanziato da Regione FVG LR 2/2011, Art.4, c.2 Research projects - Scientific Actor; Active
Fondo Ricerca di Ateneo (FRA) anno 2024 – assegnazione fondi linea A ai Dipartimenti Research projects - Participant; Active
Last update: 07-22-2024 - 09:56