Biocristallography of natural and artificial proteins
The crystallographic characterization of HIV protease inhibitor complexes and the related studies of enzyme catalysis using protein crystals are needed to investigate the catalytic mechanism. In this field, biocrystallographic studies of synthetic proteins for the development of new materials, catalysts, and biosensors are also conducted.
Reactions in HIV-1 Protease crystals
Toward the de novo design of a catalytically active helix bundle: response of a designed metalloprotein to changes in metal ion coordination determined by X-ray crystallography Angew. Chem. Int. Ed. 2003, 42, 417 |
Miniaturized heme proteins: crystal structure of Co(III)-mimochrome IV J. Biol. Inorg. Chem. 2004, 9(8), 1017 | |
Research Group
CEB Group |